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Invitrogen™ MATN3 Polyclonal Antibody

Product Code. 12828872
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Quantity:
100 μg
Unit Size:
100µg
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12828872 100 μg 100µg
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Product Code. 12828872 Supplier Invitrogen™ Supplier No. PA520727

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Description

Rabbit Polyclonal Antibody

A suggested positive control is rat thymus tissue lysate. PA5-20727 can be used with blocking peptide PEP-0841.

Matrilins (MATNs) are a family of non-collagenous extra-cellular matrix (ECM) proteins consisting of four known members that have been proposed to play key roles in modulating cellular phenotypes during chondrogenesis of mesenchymal stem cells (MSCs). MATN1 and MATN3 are expressed specifically in cartilage and are among the most up-regulated ECM proteins during chondrogenesis. MATN3 is composed of a single N-terminal von Willebrand Factor A (vWFA) domain followed by four epidermal growth factor (EGF) repeats and a coiled-coil domain whereas MATN1 is composed of two vWFA domains separated by one EGF-like domain. MATN1 or MATN3 may play a role in modulating chondrogenesis during the chondrocyte differentiation process. Mutations of this gene have been associated with variety of inherited chondrodysplasias. Recent studies show that aberrant expression and processing of MATN3 are hallmarks of conventional cartilaginous neoplasms.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MATN3
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene MATN3
Gene Accession No. O15232, O35701
Gene Alias AV009181; B14.5b; CI-B14.5b; DIPOA; EDM5; HOA; Matn3; matrilin 3; matrilin-3; NADHDH2; NDUFC2; OADIP; OS2
Gene Symbols MATN3
Host Species Rabbit
Immunogen A 13 amino acid peptide from near the center of human MATN3.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17182, 313954, 4148
Target Species Human, Mouse, Rat
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG
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