Invitrogen™ MARVELD1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5109941

Product Code. 17137873

Description

Immunogen sequence: MLPPPPRQPP PQARAARGAV RLQRPFLRSP LGVLRLLQLL AGAAFWITIA.

MARVELD1, (MARVEL domain-containing 1), is one of the MARVEL (MAL and related proteins for vesicle trafficking and membrane link) domain-containing proteins. It is a nuclear-localized protein that is widely expressed in normal human tissues. While it has been reported to be overexpressed in colon cancer, MARVELD1 protein levels are generally lower in several primary tumors including ovary, breast, kidney, bladder and liver. This lower level of MARVELD1 expression in tumors is thought to be due to a higher methylation status of the MARVELD1 promoter as treatment of MDA-MB-361 with 5-aza-2'-deoxycytidine restores MARVELD1 expression, suggesting that loss of MARVELD1 expression may contribute to tumorgenicity.

Specifications

• Antigen: MARVELD1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MARVELD1
• Gene Alias: AI504298; bA548K23.8; GB14; MARVD1; MARVEL (membrane-associating) domain containing 1; MARVEL domain containing 1; MARVEL domain-containing protein 1; Marveld1; MRVLDC1; putative MARVEL domain-containing protein 1; RP11-548K23.8
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 277010, 309375, 83742
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.77 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q7TQJ1, Q9BSK0
• Gene Symbols: MARVELD1
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-50 of human MARVELD1 (NP_1136721).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG