Invitrogen™ MARCH1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA569223

Product Code. 15857633

Description

This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%.

E3 ubiquitin-protein ligase that mediates ubiquitination of TFRC, CD86, FAS and MHC class II proteins, such as HLA-DR alpha and beta, and promotes their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. By constitutively ubiquitinating MHC class II proteins in immature dendritic cells, down-regulates their cell surface localization thus sequestering them in the intracellular endosomal system.

Specifications

• Antigen: MARCH1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MARCH1
• Gene Alias: 1-Mar; 2900024D24Rik; BB085186; E3 ubiquitin-protein ligase MARCH1; MARCH1; MARCHF1; MARCH-I; membrane associated ring finger 1; membrane associated ring-CH-type finger 1; membrane-associated ring finger (C3HC4) 1; membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase; membrane-associated RING finger protein 1; Membrane-associated RING-CH protein I; RGD1305148; RING finger protein 171; RING-type E3 ubiquitin transferase MARCH1; RNF171
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55016
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot, Surface Plasmon Resonance
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q8TCQ1
• Gene Symbols: MARCH1
• Immunogen: synthetic peptide directed towards the N terminal region of human MARCH1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG