Invitrogen™ MAPKAPK2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA517729

Product Code. 11592620

Description

It is not recommended to aliquot this antibody. This antibody is not cross-reactive with MAPKAPK-3 or -5.

MAPKAPK2 mediates p38 and ERK signaling in vivo. It is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation, and cell proliferation. MAPKAPK2 encodes a member of the Ser/Thr protein kinase family. MAPKAPK2 is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, MAPKAPK2 is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for MAPKAPK2.

Specifications

• Antigen: MAPKAPK2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MAPKAPK2
• Gene Alias: AA960234; MAP kinase-activated protein kinase 2; MAPK activated protein kinase 2; MAPK-activated protein kinase 2; MAPKAP kinase 2; Mapkapk2; MAPKAP-K2; MAPKAPK-2; mitogen-activated protein kinase-activated protein kinase 2; MK2; MK-2; Rps6kc1
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 17164, 289014, 9261
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunoprecipitation, Western Blot
• Concentration: 5 μg/mL
• Formulation: 0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5
• Gene Accession No.: P49137, P49138
• Gene Symbols: MAPKAPK2
• Immunogen: Synthetic peptide corresponding to the carboxy-terminal region of human MAPKAPK-2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Monkey
• Product Type: Antibody
• Isotype: IgG