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MAP2K3 Rabbit, anti-Human, Unconjugated, Clone: 3O10, Proteintech

Rabbit Recombinant Monoclonal Antibody

Brand:  Proteintech 80137-1-RR-20UL

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Product Code. 17281536

  • £135.00 / 20µL

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Description

Description

MAP2K3, also named as MKK3, is a member of dual specificity kinase group and serves as a specific activator of p38 MAPK with MKK6. MKK3 can be phosphorylated by cytokines and environmental stress at sites Ser189 and Thr193 by MKKK proteins (MEKK 1-4). MKK3 plays a key role in cell differentiation, motility, division and death. It has been reported that MKK3 targeting may represent an effective and potentially safe therapeutic strategy to selectively kill cancer cells in colorectal cancer patients. (PMID: 31695024, 30770795, 26805700, 8622669)

Specifications

Specifications

MAP2K3
Monoclonal
500 μg/mL
Rabbit
Primary
Human, Mouse, Rat
Western Blot, Immunofluorescence, ELISA
3O10
Unconjugated
20 μL
5606
Liquid
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