Invitrogen™ MAP2 Polyclonal Antibody

Chicken Polyclonal Antibody

Brand:  Invitrogen™ PA110005

Product Code. 11565852

Description

PA1-10005 was raised against recombinant constructs of the entire human projection domain, and so recognizes only the high molecular MAP2 forms, MAP2A and MAP2B. For long term storage, store at 4°C.

MAP2 (Microtubule Associated Protein 2) exists in two high molecular weight forms (MAP2a & MAP2b) and a low molecular weight form. The expression of MAP2 is developmentally regulated and its multiple forms arise by alternative splicing of a single gene. MAP2 is involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dendrites, implicating a role in determining and stabilizing dendritic shape during neuron development. MAP2 is useful in studies of neuron structure in normal and malignant brain tissue as well as in degenerative diseases such as Alzheimer's Disease (AD).

Specifications

• Antigen: MAP2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Map2
• Gene Alias: a730034c02; AC091465.1; DKFZp686I2148; G1-397-34; MAP 2; Map2; MAP-2; map2.S; map2a; map-2a; map2ab; MAP2B; MAP2C; MAP2R; microtubule associated protein 2; microtubule associated protein 2 S homeolog; microtubule associated protein 2; microtubule-associated protein 2; microtubule associated protein 2C; microtubule-associated protein 2; microtubule-associated protein-2; Mtap2; Mtap-2; OTTHUMP00000163916; OTTHUMP00000208143; repro4; XELAEV_18047318mg; xmap2
• Host Species: Chicken
• Purification Method: PEG precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 17756, 25595, 4133
• Content And Storage: 4°C
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot, Immunocytochemistry
• Concentration: Conc. Not Determined
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: P11137, P15146, P20357
• Gene Symbols: Map2
• Immunogen: Mix of recombinant human constructs of projection domain sequences, amino acids 235-1588.
• Quantity: 50 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgY