Maleic acid, 98+%, Thermo Scientific Chemicals

Description

Maleic acid is used as a precursor to fumaric acid, dimethyl maleate and glyoxalic acid. It is an electrophile and acts as dienophine in Diels-Alder reactions. It reacts with drugs to form more stable addition salts like indacaterol maleate, carfenazine, chlorpheniramine, pyrilamine, methylergonovine and thiethylperazine. Its maleate ion is useful in biochemistry as an inhibitor of transaminase reactions.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Maleic acid is used as a precursor to fumaric acid, dimethyl maleate and glyoxalic acid. It is an electrophile and acts as dienophine in Diels-Alder reactions. It reacts with drugs to form more stable addition salts like indacaterol maleate, carfenazine, chlorpheniramine, pyrilamine, methylergonovine and thiethylperazine. Its maleate ion is useful in biochemistry as an inhibitor of transaminase reactions.

Solubility
Soluble in water, acetone, glacial acetic acid, alcohol and concentrated sulfuric acid. Slightly soluble in diethyl ether. Insoluble in benzene and chloroform.

Notes
Incompatible with oxidizing agents, bases, reducing agents, metals and alkalis.

Specifications

Chemical Identifiers

• CAS: 110-16-7
• Molecular Formula: C4H4O4
• Molecular Weight (g/mol): 116.07
• MDL Number: MFCD00063177
• InChI Key: VZCYOOQTPOCHFL-OWOJBTEDSA-N
• Synonym: maleic acid, cis-butenedioic acid, toxilic acid, maleinic acid, malenic acid, 2z-but-2-enedioic acid, 2-butenedioic acid z, maleate, cis-1,2-ethylenedicarboxylic acid, z-butenedioic acid
• PubChem CID: 444266
• ChEBI: CHEBI:18300
• IUPAC Name: (Z)-but-2-enedioic acid
• SMILES: OC(=O)\C=C\C(O)=O

• Melting Point: 132°C to 136°C
• Beilstein: 605762
• Merck Index: 14,5703
• Solubility Information: Soluble in water,acetone,glacial acetic acid,alcohol and concentrated sulfuric acid. Slightly soluble in diethyl ether. Insoluble in benzene and chloroform.
• Formula Weight: 116.07
• Percent Purity: ≥98%
• Density: 1.59
• Quantity: 1000 g
• Flash Point: 127°C (260°F)
• Chemical Name or Material: Maleic acid

Safety and Handling

Product Identifier

• Maleic acid

Signal Word

• Danger

Hazard Category

• Acute toxicity Category 4
• Serious eye damage/eye irritation Category 1
• Skin corrosion/irritation Category 1 B
• Skin sensitiser Category 1
• Specific target organ toxicity Category 3

Hazard Statement

• H302-Harmful if swallowed.
• H312-Harmful in contact with skin.
• H314-Causes severe skin burns and eye damage.
• H317-May cause an allergic skin reaction.
• H318-Causes serious eye damage.
• H335-May cause respiratory irritation.

Precautionary Statement

• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
• P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P310-Immediately call a POISON CENTER/doctor/.

Supplemental information

• MIXTURE LIST-Contains : Maleic acid

RUO – Research Use Only