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Invitrogen™ MAK10 Polyclonal Antibody

Product Code. 12818932
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Quantity:
100 μg
Unit Size:
100µg
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12818932 100 μg 100µg
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Product Code. 12818932 Supplier Invitrogen™ Supplier No. PA520783

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Description

Rabbit Polyclonal Antibody

A suggested positive control is rat heart tissue lysate. PA5-20783 can be used with blocking peptide PEP-0897.

The MAK10 gene encodes a 733-amino acid protein with several regions of similarity to T cell receptor alpha-subunit V (variable) regions in yeast. The mammalian homologue of yeast MAK10, also known as EGAP, is one subunit of a novel N-terminal acetyltransferase (NAT) that is highly conserved among vertebrate species. It is expressed in a variety of tissues in the developing rat embryo but restricted in expression in the adult, remaining detectable only in tissues undergoing continual cell renewal or in cells responding to pathological injury. The MAK10-NAT complex is an essential regulatory enzyme controlling the function of a subset of proteins required for embryonic growth control and vessel development. This complex functionally co-assembles in mammalian cells to regulate cell proliferation and is essential for embryonic development, at least in part through the regulation of target of rapamycin (TOR) signaling events. At least two isoforms of MAK10 are known to exist.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MAK10
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene NAA35
Gene Accession No. Q5VZE5, Q6DKG0, Q6PHQ8
Gene Alias A330021G12Rik; A330027C19Rik; AI158944; bA379P1.1; C030004C14Rik; corneal wound healing related protein; corneal wound healing-related protein; corneal wound-healing-related protein; EGAP; Emb8; Embryonic growth-associated protein; embryonic growth-associated protein homolog; Mak10; MAK10 homolog, amino-acid N-acetyltransferase subunit; MAK10P; N(alpha)-acetyltransferase 35, NatC auxiliary subunit; NAA35; Nalpha acetyltransferase 35; N-alpha-acetyltransferase 35, NatC auxiliary subunit; protein MAK10 homolog; RAT52; RP11-379P1.1; T4a
Gene Symbols NAA35
Host Species Rabbit
Immunogen A 19 amino acid peptide near the amino terminus of human MAK10.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 60560, 64472, 78689
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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