Invitrogen™ MAGI2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA553073

Product Code. 15731021

Description

Immunogen sequence: AEGKRKRNKS VSNMEKASIE PPEEEEEERP VVNGNGVVVT PESSEHEDKS AGASGEMPSQ PYPAPVYSQP EELKEQMDDT KPTKPEDNEE PDPLPDNWEM A Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 92%.

Seems to act as scaffold molecule at synaptic junctions by assembling neurotransmitter receptors and cell adhesion proteins. May play a role in regulating activin-mediated signaling in neuronal cells. Enhances the ability of PTEN to suppress AKT1 activation. Plays a role in nerve growth factor (NGF)-induced recruitment of RAPGEF2 to late endosomes and neurite outgrowth. Florindo C.S., Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases. The MGC Project Team, Genome Res. 14:2121-2127(2004). Devroe E., J. Biol. Chem. 279:24444-24451(2004).

Specifications

• Antigen: MAGI2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MAGI2
• Gene Alias: activin receptor interacting protein 1; activin receptor-interacting protein 1; Acvri1; ACVRINP1; Acvrip1; AIP1; AIP-1; ARIP1; Atrophin-1-interacting protein 1; atrophin-1-interacting protein A; KIAA0705; MAGI2; MAGI-2; membrane associated guanylate kinase, WW and PDZ domain containing 2; membrane-associated guanylate kinase inverted 2; Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2; mKIAA0705; Sscam; S-SCAM; Synaptic-scaffolding molecule
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9863
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q86UL8
• Gene Symbols: MAGI2
• Immunogen: Recombinant protein corresponding to Human MAGI2. Recombinant protein control fragment (Product #RP-90781).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG