Invitrogen™ MAGEB18 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA531830

Product Code. 13486347

Description

Recommended positive controls: A549. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The melanoma-associated antigen (MAGE) family consists of a number of antigens recognized by cytotoxic T lymphocytes. The MAGE genes were initially isolated from different kinds of tumors and, based on their virtually exclusive tumor-specific expression in adult tissues, they have been used as targets for cancer immunotherapy. MAGE genes encode for tumor-rejection antigens that are expressed in tumors of different histologic types and in normal testis and placenta. MAGE-B18 (melanoma-associated antigen B18) is a 343 amino acid protein that contains one MAGE domain and may be involved in tumorigenesis. The gene encoding MAGE-B18 maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1,000 genes.

Specifications

• Antigen: MAGEB18
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MAGEB18
• Gene Alias: MAGBI; MAGE family member B18; MAGEB18; MAGE-B18 antigen; melanoma antigen family B, 18; melanoma antigen family B18; melanoma-associated antigen B18
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 286514
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q96M61
• Gene Symbols: MAGEB18
• Immunogen: Recombinant protein encompassing a sequence within the center region of human MAGEB18. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG