Invitrogen™ MAGE1 Monoclonal Antibody (6C1)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ 356300

Product Code. 10652954

Description

MAGE1 Monoclonal Antibody for Western Blot, IHC (F), IP, ELISA

Human malignant neoplasms carry rejection antigens that are recognized by the patients' autologous, tumor directed and specific, cytolytic, CD8+ T lymphocyte clones (CTL). An important group of antigens is coded by the MAGE family of genes. It was identified that melanoma associated with antigens (MAAs). Because MAGE-1 is expressed on a significant proportion of human neoplasms of various hisological tyoes (melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian, renal cell carcinomas) and not on normal tissues, the encoded antigen may serve as a marker of early detection and target for cancer immunotherapy.

Specifications

• Antigen: MAGE1
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.1% sodium azide; pH 7.4
• Gene Accession No.: P43355
• Gene Symbols: MAGEA1
• Immunogen: Full-length recombinant human MAGE-A.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a

• Applications: ELISA, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
• Clone: 6C1
• Conjugate: Unconjugated
• Gene: MAGEA1
• Gene Alias: antigen MZ2-E; antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5; cancer/testis antigen 1.1; cancer/testis antigen family 1, member 1; CD228; CT1.1; mage 1; MAGE family member A1; MAGE1; mage-1; MAGE-1 antigen; MAGE1A; MAGEA1; Mage-a1; MAP97; melanoma antigen family A 1; melanoma antigen family A, 1; melanoma antigen family A, 1 (directs expression of antigen MZ2-E); melanoma antigen family A1; melanoma antigen MAGE-1; melanoma antigen, family A, 1; melanoma-associated antigen 1; melanoma-associated antigen MZ2-E; Melanoma-associated antigen p97; melanoma-associated antigen p97, isoform 2; melanotransferrin; MELTF; membrane-bound transferrin-like protein; Mfi2; MTf; MTF1
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 4100
• Content And Storage: -20°C
• Form: Liquid