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MAGE 1 Antibody (MA454), Novus Biologicals™

Product Code. 18407161 Shop All Bio Techne Products
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0.1 mg
20 ug
Unit Size:
0.10mg
20µg
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Product Code. Quantity unitSize
18407161 20 ug 20µg
18432062 0.1 mg 0.10mg
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Product Code. 18407161 Supplier Novus Biologicals Supplier No. NBP22946920ug

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Description

Mouse Monoclonal Antibody has been used in 1 publication

MAGE 1 Monoclonal specifically detects MAGE 1 in Human, Rat, Canine samples. It is validated for ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Sandwich ELISA.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MAGE 1
Applications Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Classification Monoclonal
Clone MA454
Concentration 0.2 mg/ml
Conjugate Unconjugated
Dilution Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, ELISA 1-5ug/ml for coating, Immunohistochemistry 0.5-1ug/ml, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunoprecipitation 1-2ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml, Sandwich ELISA
Gene Accession No. P43355
Gene Alias Antigen MZ2-E, Cancer/testis antigen 1.1, cancer/testis antigen family 1, member 1, CT1.1melanoma antigen family A 1, MAGE-1 antigen, MAGE1A, MAGE1melanoma antigen MAGE-1, melanoma antigen family A, 1 (directs expression of antigen MZ2-E), melanoma-associated antigen 1, melanoma-associated antigen MZ2-E, MGC9326
Gene Symbols MAGEA1
Host Species Mouse
Immunogen Recombinant full-length human MAGE 1 protein (Uniprot: P43355)
Molecular Weight of Antigen 44 kDa
Purification Method Protein A or G purified
Quantity 20 ug
Regulatory Status RUO
Research Discipline Apoptosis, Cancer, Melanoma Cell Markers, Tumor Suppressors
Primary or Secondary Primary
Gene ID (Entrez) 4100
Test Specificity Recognizes a protein of 42-46kDa, identified as MAGE-1. This monoclonal antibody does not cross-react with MAGE-2, -3, -4, -6 -9, -10, -or -12 protein. Human malignant neoplasms carry rejection antigens that are recognized by the patients' autologous, tumor directed and specific, cytolytic, CD8+ T lymphocyte clones (CTL). The MAGE family of genes codes an important group of antigens. It was identified that melanomas and primary glial brain tumors express common melanoma associated antigens (MAAs). Because MAGE-1 is expressed on a significant proportion of human neoplasms of various histological types (melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian, renal cell carcinomas) and not on normal tissues, the encoded antigen may serve as a marker of early detection and target for cancer immunotherapy.
Target Species Human, Rat, Canine
Content And Storage Store at 4C.
Form Purified
Isotype IgG1 κ
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For Research Use Only

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