Invitrogen™ MAD4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA540596

Product Code. 15514272

Description

Peptide sequence: SLLILLEAAE YLERRDREAE HGYASVLPFD GDFAREKTKA AGLVRKAPNN Sequence homology: Cow: 93%; Dog: 93%; Guinea Pig: 93%; Human: 100%; Mouse: 86%; Rabbit: 93%; Sheep: 93%.

This gene is a member of the MAD gene family. The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues.

Specifications

• Antigen: MAD4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MXD4
• Gene Alias: 2810410A03Rik; bHLHc12; Class C basic helix-loop-helix protein 12; LOW QUALITY PROTEIN: max dimerization protein 4; MAD4; Mad4 homolog; max dimerization protein 4; Max dimerizer 4; max-associated protein 4; Max-interacting transcriptional repressor MAD4; MST149; MSTP149; MXD4
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10608
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q14582
• Gene Symbols: MXD4
• Immunogen: Synthetic peptide directed towards the N-terminal of human MXD4 (aa 5-54).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG