Invitrogen™ MAD3 Recombinant Rabbit Monoclonal Antibody (8M7B3)

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA538011

Product Code. 17276883

Description

Positive Samples: A-549, DU145, Jurkat Immunogen sequence: RRARMHIQKL EDQEQRARQL KERLRSKQQS LQRQLEQLRG LAGAAERERL RADSLDSSGL SSERSDSDQE ELEVDVESLV FGGEAELLRG F.

This gene encodes a member of the Myc superfamily of basic helix-loop-helix leucine zipper transcriptional regulators. The encoded protein forms a heterodimer with the cofactor MAX which binds specific E-box DNA motifs in the promoters of target genes and regulates their transcription. Disruption of the MAX-MXD3 complex is associated with uncontrolled cell proliferation and tumorigenesis. Transcript variants of this gene encoding different isoforms have been described.

Specifications

• Antigen: MAD3
• Classification: Recombinant Monoclonal
• Concentration: 0.46 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q9BW11
• Gene Symbols: MXD3
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 100-190 of human MAD3/MXD3 (Q9BW11).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Western Blot
• Clone: 8M7B3
• Conjugate: Unconjugated
• Gene: MXD3
• Gene Alias: 4631412E13Rik; bHLHc13; class C basic helix-loop-helix protein 13; FLJ35523; MAD3; max dimerization protein 3; Max dimerizer 3; Max-associated protein 3; Max-interacting transcriptional repressor MAD3; MGC2383; Mxd3; Myx
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 83463
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid