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Invitrogen™ LZTR2 Polyclonal Antibody

Product Code. 12859042
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Quantity:
100 μg
Unit Size:
100µg
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12859042 100 μg 100µg
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Product Code. 12859042 Supplier Invitrogen™ Supplier No. PA520903

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Rabbit Polyclonal Antibody

A suggested positive control is mouse kidney tissue lysate. PA5-20903 can be used with blocking peptide PEP-1017.

LZTR2, also known as RGPR-p117, is a member of the BTB-kelch superfamily and was initially described as a nuclear factor I (NFI) binding protein and transcriptional regulator of the regucalcin gene. LZTR2 is cytoplasmically localized but is thought to translocate to the nucleus, a process mediated by protein kinase C signaling following hormonal stimulation. Recent evidence has suggested that there is a strong correlation of single nucleotide polymorphisms of LZTR2 with obesity in the Japanese population similar to that seen with the TMEM18 gene and the GNPDA2, BDNF, FAIM2, and MC4R genes with obesity in Caucasian populations, suggesting LZTR2 may play a role in metabolism and obesity risk.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LZTR2
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene SEC16B
Gene Accession No. Q75N33, Q91XT4, Q96JE7
Gene Alias KIAA1928; Leucine zipper transcription regulator 2; LZTR2; PGPR-p117; protein SEC16 homolog B; protein transport protein Sec16B; Regucalcin gene promoter region-related protein p117; regucalcin gene promotor region related protein; RGPR; Rgpr-p117; SEC16 homolog B; SEC16 homolog B (S. cerevisiae); SEC16 homolog B, endoplasmic reticulum export factor; Sec16b; SEC16S
Gene Symbols SEC16B
Host Species Rabbit
Immunogen An 18 amino acid peptide near the carboxy terminus of human LZTR2.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 89866, 89867, 89868
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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