LZTR1 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Thermo Scientific PA564381

Product Code. 15762142

Description

Immunogen sequence: ATVYSDKLWI FAGYDGNARL NDMWTIGLQD RELTCWEEVA QSGEIPPSCC NFPVAVCRDK MFVFSGQSGA KITNNLFQFE Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.

LZTR1, a member of the BTB-kelch superfamily, was initially described as a putative transcriptional regulator based on weak homology to members of the basic leucine zipper-like family, the encoded protein subsequently has been shown to localize exclusively to the Golgi network where it may help stabilize the Golgi complex. Deletion of this gene may be associated with DiGeorge syndrome, a developmental field defect involving the third and fourth pharyngeal pouches, causing the absence of thymus and parathyroid glands, congenital cardiac abnormalities and facial dysmorphism. LZTR1 is tyrosine phosphorylated and subsequently degraded upon induction of apoptosis.

Specifications

• Antigen: LZTR1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LZTR1
• Gene Alias: 1200003E21Rik; AI591627; AW550890; BTBD29; fj87c05; leucine zipper like transcription regulator 1; leucine-zipper-like transcription regulator 1; leucine-zipper-like transcriptional regulator 1; leucine-zipper-like transcriptional regulator, 1; Lztr1; LZTR-1; MGC21205; NS10; si:dkey-98f17.2; SWNTS2; Tcfl2; wu:fj87c05; zgc:158250
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8216
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q8N653
• Gene Symbols: LZTR1
• Immunogen: Recombinant protein corresponding to Human LZTR1
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Research Use Only