Invitrogen™ LZK Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA557773

Product Code. 15795661

Description

Immunogen sequence: MHGQDIATCA NNLRYFGPAA ALRSPLSNHA QRQLPGSSPD LISTAMAADC WRSSEPDKGQ AGPWGCCQAD AYDPCLQCRP EQYGSL Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 86%.

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine-like kinase (TLK) group consists of 40 tyrosine and serine-threonine kinases such as MLK (mixed-lineage kinase), LISK (LIMK/TESK), IRAK (interleukin-1 receptor-associated kinase), Raf, RIPK (receptor-interacting protein kinase), and STRK (activin and TGF-beta receptors) families.

Specifications

• Antigen: LZK
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MAP3K13
• Gene Alias: C130026N12Rik; Leucine zipper-bearing kinase; LZK; Map3k13; MEKK13; mitogen activated protein kinase kinase kinase 13; mitogen-activated protein kinase kinase kinase 13; Mixed lineage kinase; MLK
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9175
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O43283
• Gene Symbols: MAP3K13
• Immunogen: Recombinant protein corresponding to Human LZK. Recombinant protein control fragment (Product #RP-97240).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG