CD229 Mouse anti-Human, APC, Clone: HLy9.25, Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen A15722

Product Code. 15265804

Description

CD229 (Ly9) is a cell surface receptor of the CD150 family, which includes also e.g. CD48 and CD224. Receptors of this family regulate cytokine production and cytotoxicity of lymphocytes and NK cells. High levels of CD229 are found on T and B cells, where its expression increases during their maturation. It is absent on granulocytes, bone marrow-derived dendritic cells, platelets and erythrocytes. CD229 has been also reported on mouse monocytes and NK cells. CD229 interacts homophilically through its N-terminal domain and localizes to the contact site between T cells and antigen presenting B cells during antigen-dependent immune synapse formation.

Specifications

• Antigen: CD229, Ly9
• Classification: Monoclonal
• Conjugate: APC
• Gene: LY9
• Gene Alias: RP11-312J18.1, CD229, SLAMF3, hly9, mLY9, T-lymphocyte surface antigen Ly-9, cell surface molecule Ly-9, cell-surface molecule Ly-9
• Host Species: Mouse
• Purification Method: Purified
• Regulatory Status: RUO
• Gene ID (Entrez): 4063
• Content And Storage: 4° C
• Form: Liquid

• Applications: Flow Cytometry
• Clone: HLy9.25
• Formulation: PBS with 0.2% BSA and 15mM sodium azide; pH 7.4
• Gene Accession No.: Q9HBG7
• Gene Symbols: LY9
• Immunogen: Human CD229
• Quantity: 100 Tests
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1