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  5. STEMCELL Technologies LY294002

STEMCELL Technologies LY294002

Product Code. 17150032
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Quantity:
5 mg
25 mg
Unit Size:
25mg
5mg
Product Code. Quantity unitSize
17150032 25 mg 25mg
17140032 5 mg 5mg
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Product Code. 17150032

Brand: STEMCELL Technologies 72154

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Description

PI3K/AKT pathway inhibitor; Inhibits PI3K

  • LY294002 is a PI3K inhibitor that has greater potency and selectivity than quercetin, the structure on which it is based
  • LY294002 inhibits PI3K (IC50 = 1.4 μM) and also shows activity against CK2, but not PI4K, EGFR, PDGFR, MAPK, PKA, or PKC
  • (Davies et al.), Vlahos et al.)
  • Suppresses proliferation and self-renewal of mouse embryonic stem (ES) cells (Lianguzova et al.), Paling et al.)
  • Promotes differentiation to insulin-producing cells from mouse ES cells (Hori et al.)
  • Inhibits myotube formation from myoblasts (Coolican et al.), Jiang et al.)

Specifications

CAS 154447-36-6
Quantity 25 mg
Molecular Formula C19H17NO3
Purity ≥98%
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