Invitrogen™ Ly-6G Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA585890

Product Code. 16372795

Description

Ly-6G Polyclonal Antibody for Western Blot

Ly6G (Lymphocyte antigen 6 complex locus G6D) is a component of the myeloid differentiation antigen Gr-1, together with Ly6C. The Ly6G protein has a molecular weight of approximately 21-25 kDa and is expressed by myeloid derived cells in the bone marrow. Ly6G is a good marker for detection of peripheral neutrophils, monocytes and granulocytes. Expression of Gr-1 in bone marrow correlates with granulocyte differentiation and maturation. The physiological role of Ly6G remains unclear but studies have shown its involvement in anti-tumor response, and studies with neutrophils suggest that Ly6G ligation may have an inhibitory effect on local immune responses.

Specifications

• Antigen: Ly-6G
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Ly6g
• Gene Alias: Gr1; Gr-1; Ly6g; Ly-6G; ly-6G.1; lymphocyte antigen 6 complex, locus G; lymphocyte antigen 6G
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 546644
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.2% BSA, 25% Glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P35461
• Gene Symbols: Ly6g
• Immunogen: Synthetic peptide within mouse Ly-6G aa 1-50.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG