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LY 345899, MedChemExpress

Product Code. 16483648
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Product Code. 16483648 Supplier Medchem Express Supplier No. HY101943

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Description

MedChemExpress LY 345899 is a Folate analog and is a methylene tetrahydrofolate dehydrogenase (MTHFD1; DC301) and MTHFD2 inbhibitor with IC50 values of 96 nM and 663 nM, respectively and a Ki of 18 nM for MTHFD1.

LY 345899 is a Folate analog and is a methylene tetrahydrofolate dehydrogenase (MTHFD1

Specifications

Chemical Name or Material LY 345899
Physical Form Solid
CAS 10538-99-5
Color Light Yellow
Quantity 10 mg
Purity Grade Notes Research
Molecular Formula C20H21N7O7
For Use With (Application) Cancer-programmed cell death
Solubility Information DMSO : 125 mg/mL (265.16 mM; Need ultrasonic)
SMILES O=C(O)[C@@H](NC(C1=CC=C(N2C(N3C4=C(NC(N)=NC4=O)NCC3C2)=O)C=C1)=O)CCC(O)=O
Molecular Weight (g/mol) 471.42
Formula Weight 471.42
Percent Purity 98.0%
Grade Research
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Research purposes only

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