Invitrogen™ Ly-108 Recombinant Rabbit Monoclonal Antibody (105), PE

Rabbit Recombinant Monoclonal Antibody

Product Code	Brand	Quantity
30535493	Invitrogen™ MA560346	100 Tests
30534171	Invitrogen™ MA560347	25 Tests

Description

Ly-108 Recombinant Monoclonal Antibody for Flow

Ly108, the mouse homologue of human SLAMF6 (signaling lymphocyte activation molecule family member 6), is expressed on NK cells, B cells, and T cells. Engagement of the Ly108 receptor enhances NK cell activity and increases the expression of IFN-gamma. This receptor plays a role in the inability of NK cells to kill Epstein Barr virus-infected B cells in X-linked lymphoproliferative disease. In Ly108 knock-out mice, CD4+ T cells show a diminished ability to produce IL-4 and exhibit defective neutrophil functions, indicating the importance of Ly108 in immune regulation and cellular function. Overall, Ly108 is crucial for modulating immune responses and maintaining effective immune cell activity.

Specifications

• Antigen: Ly-108
• Concentration: 0.1 mg/mL
• Applications: Flow Cytometry
• Conjugate: PE
• Host Species: Rabbit
• Regulatory Status: RUO
• Formulation: PBS with 0.5% BSA and 0.09% sodium azide
• Gene Accession No.: Q96DU3
• Gene ID (Entrez): 114836
• Immunogen: Recombinant Human Ly108/SLAMF6 protein (Met1-Met226).
• Product Type: Antibody

• Clone: 105
• Content And Storage: 4°C, store in dark, DO NOT FREEZE!
• Classification: Recombinant Monoclonal
• Form: Liquid
• Isotype: IgG
• Target Species: Human
• Gene: SLAMF6
• Gene Alias: Activating NK receptor; CD352; KAL1; KAL1b; KALI; KALIb; Ly108; Lymphocyte antigen 108; natural killer-, T- and B-cell antigen; NK-T-B-antigen; NTBA; NTB-A; NTBA receptor; RGD1561848; SF2000; SLAM family member 6; Slamf6; UNQ6123/PRO20080
• Gene Symbols: SLAMF6
• Primary or Secondary: Primary
• Purification Method: Protein A