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Invitrogen™ LXR beta Polyclonal Antibody

Product Code. 12838942
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Quantity:
100 μg
Unit Size:
100µg
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Product Code. Quantity unitSize
12838942 100 μg 100µg
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Product Code. 12838942 Supplier Invitrogen™ Supplier No. PA520886

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Description

Rabbit Polyclonal Antibody

A suggested positive control is human lung tissue lysate. PA5-20886 can be used with blocking peptide PEP-1000.

The liver X receptors, LXRA and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors and regulate expression of target genes containing LXR response elements.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LXR beta
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene NR1H2
Gene Accession No. P55055, Q60644, Q62755
Gene Alias AI194859; liver X nuclear receptor beta; liver X receptor beta; LX receptor beta; LXR; LXR beta; LXRB; LXR-b; LXRbeta; NER; NER1; NER-I; Nr1h2; NR1H2 protein; nuclear orphan receptor LXR-beta; nuclear receptor NER; Nuclear receptor subfamily 1 group H member 2; nuclear receptor subfamily 1, group H, member 2; OR-1; Orphan nuclear receptor OR-1; oxysterols receptor LXR-beta; Retinoid X receptor-interacting protein No.15; RIP15; steroid hormone-nuclear receptor NER; ubiquitous receptor; ubiquitously-expressed nuclear receptor; ubiquitously-expressed nuclear receptor 2; UNR; Unr2; UR
Gene Symbols NR1H2
Host Species Rabbit
Immunogen A 14 amino acid peptide from near the amino terminus human LXR-B.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22260, 58851, 7376
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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