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Invitrogen™ LSM11 Polyclonal Antibody

Description
Recommended positive controls: A431. Predicted reactivity: Mouse (96%), Rat (96%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
LSm11 is a 360 amino acid protein that localizes to the nucleus and belongs to the LSm subfamily of snRNP Sm proteins. Containing an N-terminal domain that is necessary for pre-mRNA cleavage, LSm11 functions to binds specifically to U7 snRNA and is thought to play a role in cell cycle regulation and cell growth. The gene encoding LSm11 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
Specifications
Specifications
| Antigen | LSM11 |
| Applications | Western Blot |
| Classification | Polyclonal |
| Concentration | 0.73 mg/mL |
| Conjugate | Unconjugated |
| Formulation | 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7 |
| Gene | LSM11 |
| Gene Accession No. | P83369 |
| Gene Alias | 2210404M20Rik; AV079530; FLJ38273; Lsm11; LSM11, U7 small nuclear RNA associated; RGD1565523; U7 snRNA-associated Sm-like protein LSm11; U7 snRNP-specific Sm-like protein LSM11 |
| Gene Symbols | LSM11 |
| Show More |
Product Title
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