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Invitrogen™ LRRTM2 Polyclonal Antibody

Product Code. 12849242
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Quantity:
100 μg
Unit Size:
100µg
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12849242 100 μg 100µg
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Product Code. 12849242 Supplier Invitrogen™ Supplier No. PA521097

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Rabbit Polyclonal Antibody

A suggested positive control is SK-N-SH cell lysate. PA5-21097 can be used with blocking peptide PEP-1211.

The Leucine-rich repeat transmembrane neuronal proteins (LRRTMs) are differentially expressed in the nervous system and were recently found to instruct presynaptic and mediate postsynaptic glutamatergic differentiation, with LRRTM1 and LRRTM2 most potent at inducing presynaptic differentiation. Each LRRTM protein is a type I transmembrane containing ten extracellular leucine-rich repeats and a short intracellular tail and has a developmentally regulated pattern distinct from all others. LRRTM2 interacts with PSD-95 and regulates the surface expression of AMPA receptors. LRRTM2 also functions as a neurexin ligand, binding both Neurexin 1-alpha and -beta, suggesting that LRRTM2-Neurexin1 interaction plays a critical role in regulatory excitatory synapse development.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LRRTM2
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene LRRTM2
Gene Accession No. D4A7P2, O43300, Q8BGA3
Gene Alias AI851755; BB129880; C630011A14Rik; KIAA0416; leucine rich repeat transmembrane neuronal 2; leucine-rich repeat neuronal 2 protein; leucine-rich repeat transmembrane neuronal 2 protein; leucine-rich repeat transmembrane neuronal protein 2; LRRN2; LRRTM2; mKIAA0416
Gene Symbols LRRTM2
Host Species Rabbit
Immunogen A 17 amino acid peptide near the carboxy terminus of human LRRTM2.
Purification Method Antigen Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 107065, 26045, 685472
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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