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Invitrogen™ LRRC19 Polyclonal Antibody

Product Code. 12839062 Shop All Thermo Scientific Products
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Quantity:
100 μg
Unit Size:
100µg
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12839062 100 μg 100µg
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Product Code. 12839062 Supplier Invitrogen™ Supplier No. PA520914

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Description

Rabbit Polyclonal Antibody

A suggested positive control is K562 cell lysate. PA5-20914 can be used with blocking peptide PEP-1028.

LRRC19 is a member of the extracellular leucine-rich repeat superfamily, a family of proteins that are thought to have diverse functions such as cell adhesion, signaling, and innate immunity. LRRC19 is closely related to the Toll-like receptors (TLRs), especially TLR3. LRRC19 does not contain a cytoplasmic Toll/IL-1 receptor (TIR) domain, but can activate NF-kappa-B and induce the production of proinflammatory cytokines after stimulation with the TLR3 and other TLR ligands, suggesting that LRRC19 may play a role in the recognition and the response to certain pathogenic microorganisms. LRRC19 has also been suggested to be a potential biomarker for pancreatic tumor sensitivity to the anti-cancer, small molecule Src inhibitor AZD0530.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LRRC19
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene LRRC19
Gene Accession No. Q8BZT5, Q9H756
Gene Alias 9130022A01Rik; AI314124; AL022954; AW261791; leucine rich repeat containing 19; leucine-rich repeat-containing protein 19; LRRC19
Gene Symbols LRRC19
Host Species Rabbit
Immunogen A 17 amino acid peptide near the carboxy terminus of human LRRC19.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100061, 64922
Target Species Human, Mouse
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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