Invitrogen™ LRP5 Polyclonal Antibody

Sheep Polyclonal Antibody

Brand:  Invitrogen™ PA5149231

Product Code. 30535208

Description

Reconstitute at 0.2 mg/mL in sterile PBS.

LDL related proteins, LRP 5 and LRP 6, are members of the LDL receptor superfamily, which were found to be involved in the canonical Wnt signaling pathway. Mammalian LRP 6 was shown to bind to Wnt 1 and enhance Wnt-induced developmental processes in Xenopus embryos. Mice lacking LRP 6 exhibited developmental defects that are similar to those caused by deficiencies in various Wnt proteins. Recent work also shows that Wnt proteins induce the binding of LRP 5 to Axin, leading Axin degradation and beta catenin stabilization.

Specifications

• Antigen: LRP5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LRP5
• Gene Alias: BMND1; EVR1; EVR4; HBM; HGNC:6697; LDL receptor related protein 5; low density lipoprotein receptor-related protein 5; low density lipoprotein receptor-related protein 7; low-density lipoprotein receptor-related protein 5; Low-density lipoprotein receptor-related protein 7; LR3; Lrp5; LRP-5; LRP7; LRP-7; mKIAA4142; OPPG; OPS; OPTA1; VBCH2
• Host Species: Sheep
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4041
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Lyophilized

• Applications: Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with trehalose and no preservative
• Gene Accession No.: O75197
• Gene Symbols: LRP5
• Immunogen: E. coli-derived recombinant human LRP-5, Phe1422-Ser1615.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG