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Invitrogen™ LRFN5 Polyclonal Antibody
Description
A suggested positive control is EL4 cell lysate. PA5-20700 can be used with blocking peptide PEP-0815.
LRFN5 is one of a family of five transmembrane glycoproteins that are highly expressed in neuronal tissues. LRFN proteins share leucine-rich repeat (LRR)-immunoglobulin-like (Ig)-fibronectin type III (Fn)-transmembrane domain structure with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family of proteins. Expression of LRFN1, -3, and -4 mRNA was detected in embryonic neuronal cells, while LRFN2 and LRFN5 expression was primarily restricted to more mature cells. LRFN1, -2, and -4 bound to PDZ domains of postsynaptic PSD95, re-distributing PSD95 to the cell periphery. It has been suggested that the Lrfn proteins play a role in the developing and/or mature vertebrate nervous system.
Specifications
Specifications
| Antigen | LRFN5 |
| Applications | Immunohistochemistry, Western Blot |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 0.02% sodium azide |
| Gene | LRFN5 |
| Gene Accession No. | D4A1J9, Q8BXA0, Q96NI6 |
| Gene Alias | AI427653; AI604817; C130061B21; C14orf146; fibronectin type III, immunoglobulin and leucine rich repeat domains 8; FIGLER8; Kiaa4208; leucine rich repeat and fibronectin type III domain containing 5; leucine-rich repeat and fibronectin type-III domain-containing protein 5; LRFN5; mKIAA4208; SALM5 |
| Gene Symbols | LRFN5 |
| Show More |
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