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Invitrogen™ LRFN4 Polyclonal Antibody
Description
A suggested positive control is rat brain tissue lysate. PA5-20699 can be used with blocking peptide PEP-0814.
LRFN4 is one of a family of five transmembrane glycoproteins that are highly expressed in neuronal tissues. LRFN proteins share leucine-rich repeat (LRR)-immunoglobulin-like (Ig)-fibronectin type III (Fn)-transmembrane domain structure with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family of proteins. Expression of LRFN1, -3, and -4 mRNA was detected in embryonic neuronal cells, while Lrfn2 and Lrfn5 expression was primarily restricted to more mature cells. LRFN1, -2, and -4 bound to PDZ domains of postsynaptic PSD95, re-distributing PSD95 to the cell periphery. It has been suggested that the Lrfn proteins play a role in the developing and/or mature vertebrate nervous system. At least two isoforms of LRFN4 are known to exist.
Specifications
Specifications
| Antigen | LRFN4 |
| Applications | Immunohistochemistry, Western Blot |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 0.02% sodium azide |
| Gene | LRFN4 |
| Gene Accession No. | D4ABX8, Q6PJG9, Q80XU8 |
| Gene Alias | BC023156; fibronectin type III, immunoglobulin and leucine rich repeat domains 6; FIGLER6; leucine rich repeat and fibronectin type III domain containing 4; leucine-rich repeat and fibronectin type-III domain-containing protein 4; Lrfn4; Salm3; SALM3.; synaptic adhesion-like molecule 3 |
| Gene Symbols | LRFN4 |
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Product Title
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