Invitrogen™ LRFN4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA520699

Product Code. 12848842

Description

A suggested positive control is rat brain tissue lysate. PA5-20699 can be used with blocking peptide PEP-0814.

LRFN4 is one of a family of five transmembrane glycoproteins that are highly expressed in neuronal tissues. LRFN proteins share leucine-rich repeat (LRR)-immunoglobulin-like (Ig)-fibronectin type III (Fn)-transmembrane domain structure with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family of proteins. Expression of LRFN1, -3, and -4 mRNA was detected in embryonic neuronal cells, while Lrfn2 and Lrfn5 expression was primarily restricted to more mature cells. LRFN1, -2, and -4 bound to PDZ domains of postsynaptic PSD95, re-distributing PSD95 to the cell periphery. It has been suggested that the Lrfn proteins play a role in the developing and/or mature vertebrate nervous system. At least two isoforms of LRFN4 are known to exist.

Specifications

• Antigen: LRFN4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LRFN4
• Gene Alias: BC023156; fibronectin type III, immunoglobulin and leucine rich repeat domains 6; FIGLER6; leucine rich repeat and fibronectin type III domain containing 4; leucine-rich repeat and fibronectin type-III domain-containing protein 4; Lrfn4; Salm3; SALM3.; synaptic adhesion-like molecule 3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 225875, 688721, 78999
• Content And Storage: Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: D4ABX8, Q6PJG9, Q80XU8
• Gene Symbols: LRFN4
• Immunogen: a 14amino acid peptide near the carboxy terminus of human LRFN4.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG