missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Invitrogen™ LRFN1 Polyclonal Antibody
Description
A suggested positive control is human brain tissue lysate. PA5-20698 can be used with blocking peptide PEP-0813.
LRFN1 is one of a family of five transmembrane glycoproteins that are highly expressed in neuronal tissues. LRFN proteins share leucine-rich repeat (LRR)-immunoglobulin-like (Ig)-fibronectin type III (Fn)-transmembrane domain structure with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family of proteins. Expression of LRFN1, -3, and -4 mRNA was detected in embryonic neuronal cells, while Lrfn2 and Lrfn5 expression was primarily restricted to more mature cells. LRFN1, -2, and -4 bound to PDZ domains of postsynaptic PSD95, re-distributing PSD95 to the cell periphery. It has been suggested that the Lrfn proteins play a role in the developing and/or mature vertebrate nervous system. At least two isoforms of LRFN1 are known to exist.
Specifications
Specifications
| Antigen | LRFN1 |
| Applications | Immunohistochemistry, Western Blot |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 0.02% sodium azide |
| Gene | LRFN1 |
| Gene Accession No. | P0C7J6, Q2WF71, Q9P244 |
| Gene Alias | BC004018; CTC-246B18.8; KIAA1484; leucine rich repeat and fibronectin type III domain containing 1; leucine-rich repeat and fibronectin type III domain-containing protein 1; Lrfn1; Salm2; Semo1; Synaptic adhesion-like molecule 2; synaptic differentiation enhancing molecule 1; synaptic differentiation-enhancing molecule 1 |
| Gene Symbols | LRFN1 |
| Show More |
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?