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  5. Tocris Bioscience™ LP 99

Tocris Bioscience™ LP 99
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Product Code. p-7161649
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Quantity:
5 mg
25 mg
Unit Size:
25mg
5mg
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Product Code. 18788446

Brand: Tocris Bioscience™ 5496/25

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Description

Selective BRD7 and BRD9 inhibitor (Kd values are 99 and 909 nM, respectively)

LP 99 is a selective BRD7 and BRD9 inhibitor (Kd values are 99 and 909 nM, respectively) that exhibits selectivity for BRD7/9 over a panel of 48 bromodomains (at 10 μM). LP 99 inhibits interactions with histones H3.3 and H4 at low micromolar concentrations, and decreases the level of IL-6 secreted from LPS-stimulated THP-1 cells, in vitro. A negative control for LP 99, ent-LP 99 (Cat.No. 5497), is also available.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material N-[(2R,3S)-2-(4-Chlorophenyl)-1-(1,2-dihydro-1,4-dimethyl-2-oxo-7-quinolinyl)-6-oxo-3-piperidinyl]-2-methyl-1-propanesulfonamide
CAS 1808951-93-0
Quantity 25 mg
Molecular Formula C26H30ClN3O4S
Formula Weight 516.05
Purity 98%
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