Invitrogen™ LOXL4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA558036

Product Code. 15785921

Description

Immunogen sequence: RRHRGYLSET VSNALGPQGR RLEEVRLKPI LASAKQHSPV TEGAVEVKYE GHWRQVCDQG WTMN Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 91%.

This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.

Specifications

• Antigen: LOXL4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LOXL4
• Gene Alias: 4833426I20Rik; FLJ21889; Loxc; LOXL4; Lysyl oxidase homolog 4; lysyl oxidase like 4; lysyl oxidase related C; lysyl oxidase-like 4; lysyl oxidase-like 4 pseudogene; lysyl oxidase-like protein 4; Lysyl oxidase-related protein C
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 84171
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q96JB6
• Gene Symbols: LOXL4
• Immunogen: Recombinant protein corresponding to Human LOXL4. Recombinant protein control fragment (Product #RP-97095).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG