Invitrogen™ LOX-1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA595063

Product Code. 16369781

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human prostatic carcinoma tissue (PCT), human cervical carcinoma tissue (CCAT), human gallbladder carcinoma tissue (GBCT), human intrahepatic cholangiocarcinom paracancerous tissue (ICCP). Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

LOX-1 (lectin-like oxidized LDL receptor -1) is a 40-50 kDa type II membrane glycoprotein class E scavenger receptor expressed by endothelial cells, macrophages, activated platelets and smooth muscle cells. LOX-1 binds to a wide range of ligands, including oxidized low-density lipoprotein (oxLDL), hypochlorite modified high-density lipoprotein (HDL), aged /apoptotic cells, activated platelets and bacteria, reflecting its versatile physiological functions.

Specifications

• Antigen: LOX-1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: OLR1
• Gene Alias: CLEC8A; C-type lectin domain family 8 member A; hLOX 1; hLOX1; hLOX-1; lectin-like oxidized LDL receptor; lectin-like oxidized LDL receptor 1; lectin-like oxidized low-density lipoprotein receptor; Lectin-like oxidized low-density lipoprotein receptor-1; lectin-like oxLDL receptor 1; lectin-type oxidized LDL receptor 1; LOX 1; LOX1; LOX-1; LOXIN; Oldlr1; Oldr1; OLR1; ox LDL receptor 1; oxidised low density lipoprotein (lectin-like) receptor 1; oxidized low density lipoprotein (lectin-like) receptor 1; oxidized low density lipoprotein receptor 1; oxidized low-density lipoprotein receptor 1; Oxidized low-density lipoprotein receptor 1, soluble form; ox-LDL receptor 1; Scare1; scavenger receptor class E, member 1; sLOX 1; SLOX1; soluble LOX 1; SR-EI
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4973
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Western Blot
• Concentration: 500 μg/mL
• Formulation: PBS with 5mg BSA and 0.05mg sodium azide, 0.05mg thimerosal
• Gene Accession No.: P78380
• Gene Symbols: OLR1
• Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human LOX 1 (1-16aa MTFDDLKIQTVKDQPD).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG