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Tocris Bioscience™ Lovastatin
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Product Code. 18064802
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
Product Code. Quantity unitSize
18064802 10 mg 10mg
18014072 50 mg 50mg
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Product Code. 18064802

Brand: Tocris Bioscience™ 1530/10

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102.80 GBP valid until 2026-03-31
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This item is not returnable. View return policy

Description

Potent HMG-CoA reductase inhibitor

Potent, competitive inhibitor of HMG-CoA reductase (Ki = 0.6 nM) therefore decreases cholesterol biosynthesis, in vitro and in vivo. Indirectly inhibits Rho-GTPase activity by depleting intracellular pool of isoprene residues. Decreases CDK2, 4, 6 and cyclin E levels and induces G1 arrest and apoptosis in tumor cell lines in vitro. Inactive lactam prodrug of lovastatin hydroxy acid, naturally bioactivated in vivo following oral administration.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 75330-75-5
Molecular Formula C24H36O5

Specifications

Quantity 10 mg
Formula Weight 404.54
Purity >98%
Molecular Weight (g/mol) 404.55
Chemical Name or Material Lovastatin
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