Loratadine, 98+%, Thermo Scientific™

A nonsedating-type histamine H1-receptor antagonist

Brand:  Thermo Scientific Alfa Aesar J60190.06

Product Code. 15482999

Description

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

Applications
Loratadine, is used as a peripheral histamine H1 receptor agonist. It is also used as an orally active antiallergic agent. It is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and Dyestuff.

Solubility
It is soluble in DMSO (50 mg/ml), ethanol (77 mg/ml at 25°C), water (<1mg/mL at 25°C), chloroform, and methanol.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 - 8°C. Keep away fom strong oxidizing agents.

Chemical Identifiers

• CAS: 79794-75-5
• Molecular Weight (g/mol): 382.888
• InChI Key: JCCNYMKQOSZNPW-UHFFFAOYSA-N
• PubChem CID: 3957
• SMILES: CCOC(=O)N1CCC(=C2C3=C(CCC4=C2N=CC=C4)C=C(C=C3)Cl)CC1

• Molecular Formula: C22H23ClN2O2
• MDL Number: MFCD00672869
• Synonym: loratadine, claritin, loratidine, alavert, clarityn, lisino, clarityne, loracert, loradex, bonalerg
• IUPAC Name: ethyl 4-(8-chloro-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridin-11-ylidene)piperidine-1-carboxylate

Specifications

• CAS: 79794-75-5
• MDL Number: MFCD00672869
• Merck Index: 14,5578
• Solubility Information: It is soluble in DMSO (50mg/ml),ethanol (77mg/ml at 25°C),water (<1mg/ml at 25°C),chloroform,and methanol.
• SMILES: CCOC(=O)N1CCC(=C2C3=C(CCC4=C2N=CC=C4)C=C(C=C3)Cl)CC1
• Molecular Weight (g/mol): 382.888
• Formula Weight: 382.88
• Chemical Name or Material: Loratadine

• Molecular Formula: C22H23ClN2O2
• Quantity: 5g
• Synonym: loratadine, claritin, loratidine, alavert, clarityn, lisino, clarityne, loracert, loradex, bonalerg
• InChI Key: JCCNYMKQOSZNPW-UHFFFAOYSA-N
• IUPAC Name: ethyl 4-(8-chloro-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridin-11-ylidene)piperidine-1-carboxylate
• PubChem CID: 3957
• Percent Purity: ≥98%