Invitrogen™ LONP1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA551692

Product Code. 15719650

Description

Immunogen sequence: VEEKIKQTHR KYLLQEQLKI IKKELGLEKD DKDAIEEKFR ERLKELVVPK HVMDVVDEEL SKLGLLDNHS SEFNVTRNYL DWLTSIPWGK YSNENLDLAR AQAVLEEDHY GMEDVKKRIL EFIAVSQLRG STQGKILCFY GP Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 95%.

This gene encodes a mitochondrial matrix protein that belongs to the Lon family of ATP-dependent proteases. This protein mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides in the mitochondrial matrix. It may also have a chaperone function in the assembly of inner membrane protein complexes, and participate in the regulation of mitochondrial gene expression and maintenance of the integrity of the mitochondrial genome. Decreased expression of this gene has been noted in a patient with hereditary spastic paraplegia. Alternatively spliced transcript variants have been found for this gene.

Specifications

• Antigen: LONP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LONP1
• Gene Alias: 1200017E13Rik; CODASS; h LonHS; HAMAP-Rule:MF_03120}; hLON; hLON ATP-dependent protease; Lon; lon peptidase 1, mitochondrial; lon protease homolog, mitochondrial; lon protease homolog, mitochondrial {ECO:0000255; Lon protease-like protein; lon protease-like protein {ECO:0000255; LONHs; LONP; LONP {ECO:0000255; LONP1; Mitochondrial ATP-dependent protease Lon; mitochondrial ATP-dependent protease Lon {ECO:0000255; mitochondrial lon protease-like protein; PIM1; protease, serine, 15; Prss15; Serine protease 15; serine protease 15 {ECO:0000255
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 170916, 74142, 9361
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.30 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P36776, Q8CGK3, Q924S5
• Gene Symbols: LONP1
• Immunogen: Recombinant protein corresponding to Human LONP1. Recombinant protein control fragment (Product #RP-99402).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG