Invitrogen™ LMTK3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA585019

Product Code. 16381965

Description

Immunogen sequence: CSCLPLERGD AVAGWGGHPA LGCPHPPEDD SSLRAERGSL ADLPMAPPAS APPEFLDP Highest antigen sequence indentity to the following orthologs: Rat - 34%, Mouse - 91%.

Protein kinase which phosphorylates ESR1 (in vitro) and protects it against proteasomal degradation. May also regulate ESR1 levels indirectly via a PKC-AKT-FOXO3 pathway where it decreases the activity of PKC and the phosphorylation of AKT, thereby increasing binding of transcriptional activator FOXO3 to the ESR1 promoter and increasing ESR1 transcription (PubMed:21602804). Involved in endocytic trafficking of N-methyl-D-aspartate receptors (NMDAR) in neurons. [UniProt].

Specifications

• Antigen: LMTK3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LMTK3
• Gene Alias: Aatyk3; Apoptosis-associated tyrosine kinase 3; BC059845; KIAA1883; Lemur tyrosine kinase 3; LMR3; Lmtk3; LOC691056; PPP1R101; protein phosphatase 1, regulatory subunit 101; serine/threonine-protein kinase LMTK3; similar to 5E5 antigen; TYKLM3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 114783, 381983
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.4 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q5XJV6, Q96Q04
• Gene Symbols: LMTK3
• Immunogen: Recombinant protein corresponding to Human LMTK3. Recombinant protein control fragment (Product #RP-108287).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG