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  6. LMNB2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

LMNB2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Product Code. 16867583 Shop All Proteintech Products
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150 μL
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20µL
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16867583 20 μL 20µL
16857583 150 μL 150µL
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Product Code. 16867583 Supplier Proteintech Supplier No. 108951AP20UL

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Description

Rabbit Polyclonal Antibody

Nuclear lamins form a network of intermediate-type filaments at the nucleoplasmic site of the nuclear membrane. Two main subtypes of nuclear lamins can be distinguished, i. e. A-type lamins and B-type lamins. The A-type lamins comprise a set of three proteins arising from the same gene by alternative splicing, i. e. lamin A, lamin C and lamin Adel 10, while the B-type lamins include two proteins arising from two distinct genes, i. e. lamin B1 and lamin B2. Recent evidence has revealed that mutations in A-type lamins give rise to a range of rare but domit genetic disorders, including Emery-Dreifuss muscular dystrophy, dilated cardiomyopathy with conduction-system disease and Dunnigan-type familial partial lipodystrophy. In addition, the expression of A-type lamins coincides with cell differentiation and as A-type lamins specifically interact with chromatin, a role in the regulation of differential gene expression has been suggested for A-type lamins.

Specifications

Antigen LMNB2
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Immunofluorescence, Immunocytochemistry
Classification Polyclonal
Concentration 0.13 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene LMNB2
Gene Accession No. P21619, Q03252
Gene Alias LAMB2, lamin B2, LMN2, LMNB2
Gene Symbols LMNB2
Host Species Rabbit
Immunogen LMNB2 Fusion Protein Ag1335
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16907, 299625, 84823
Target Species Rat, Mouse, Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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