Invitrogen™ LMAN1 Monoclonal Antibody (2B4)

Rat Monoclonal Antibody

Brand:  Invitrogen™ MA549065

Product Code. 17966261

Description

The monoclonal antibody 2B4 is a calcium-dependent antibody.

The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished.

Specifications

• Antigen: LMAN1
• Classification: Monoclonal
• Concentration: 100 μg/mL
• Formulation: PBS with 0.1% BSA and 0.02% sodium azide
• Gene Accession No.: Q9D0F3
• Gene Symbols: LMAN1
• Immunogen: Purified mouse MBL-A.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG1

• Applications: Inhibition Assays, Western Blot
• Clone: 2B4
• Conjugate: Unconjugated
• Gene: LMAN1
• Gene Alias: 2610020P13Rik; AI326273; AU043785; C730041J05; EGK_09725; endoplasmic reticulum-golgi intermediate compartment protein 53; ERGIC53; ERGIC-53; ER-Golgi intermediate compartment 53 kDa protein; F5F8D; FMFD1; Gp58; intracellular mannose-specific lectin MR60; Lectin mannose-binding 1; lectin, mannose binding 1; lectin, mannose-binding, 1; LMAN1; MCFD1; MR60; P58; Protein ERGIC-53
• Host Species: Rat
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 70361
• Content And Storage: 4°C
• Form: Liquid