Invitrogen™ LLGL2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5109920

Product Code. 17127853

Description

Immunogen sequence: RQVFVKCTLH PSDQLALEGP LSRVKSLKKS LRQSFRRMRR SRVSSHKRRP GGPTGEAQAQ AVNIKAERTG LQNMELAPVQ RKIEARSAED SFTGFVRTLY FADTYLRDSS RHCPSLWAGT NGGTVYAFSL RVPPAERRTD EPVRAEQAKE IQLMHRAPVV GILVLDGHNV PLPEPLEVAH DLSKSPDMQG SHQLLVVSEE.

LLGL1 is a protein that is similar to a tumor suppressor in Drosophila. The protein is part of a cytoskeletal network and is associated with nonmuscle myosin II heavy chain and a kinase that specifically phosphorylates this protein at serine residues. The gene for LLGL1 is located within the Smith-Magenis syndrome region on chromosome 17. LLGL2 is a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells.

Specifications

• Antigen: LLGL2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LLGL2
• Gene Alias: 9130006H11Rik; HGL; Hugl-2; human giant larvae homolog; lethal giant larvae homolog 2; lethal giant larvae homolog 2 (Drosophila); lethal giant larvae homolog 2, scribble cell polarity complex component; lethal giant larvae-like protein 2; Lethal(2) giant larvae protein homolog 2; LGL2; LLGL scribble cell polarity complex component 2; Llgl2; LLGL2, scribble cell polarity complex component; Llglh2; RGD1560307
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 217325, 360661, 3993
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 2.15 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q3TJ91, Q6P1M3
• Gene Symbols: LLGL2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 620-819 of mouse LLGL2 (NP_663413.2).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG