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Invitrogen™ LKB1 Polyclonal Antibody

Product Code. 12828512
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Quantity:
100 μg
Unit Size:
100µg
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Product Code. Quantity unitSize
12828512 100 μg 100µg
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Product Code. 12828512 Supplier Invitrogen™ Supplier No. PA520325

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Description

Rabbit Polyclonal Antibody

Despite the predicted molecular weight, LKB1 often migrates at a higher molecular weight in SDS-PAGE. A suggested positive control is PC-3 cell lysate. PA5-20325 can be used with blocking peptide PEP-0445.

LKB1 (also known as STK11 - Serine/threonine-protein kinase STK11), a member of the serine/threonine kinase family, is a tumor suppressor. LKB1 physically associates with p53 and regulates specific p53 dependent apoptosis pathways. LKB1 is present in both the cytoplasm and nucleus of living cells and translocates to mitochondria during apoptosis. LKB1 functions as a master upstream protein kinase, regulating AMPK related kinases as well as AMPK. Mutations in LKB1 gene are associated with Peutz Jeghers syndrome.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LKB1
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene STK11
Gene Accession No. Q15831, Q9WTK7
Gene Alias AA408040; CAMK group; CAMKL family; hLKB1; liver kinase B1; Liver kinase B1 homolog; LKB 1; LKB1; LKB-1; LKB1(S); Par-4; PJS; polarization-related protein LKB1; R75140; renal carcinoma antigen NY-REN-19; serine/threonine kinase 11; serine/threonine-protein kinase 11; serine/threonine-protein kinase LKB1; serine/threonine-protein kinase STK11; STK11
Gene Symbols STK11
Host Species Rabbit
Immunogen A 15 amino acid peptide from near the carboxy terminus of human LKB1.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20869, 6794
Target Species Human, Mouse
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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