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  5. Tocris Bioscience™ LJI308

Tocris Bioscience™ LJI308
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Product Code. 18787156
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25 mg
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18787156 25 mg 25mg
18788046 5 mg 5mg
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Product Code. 18787156 Supplier Tocris Bioscience™ Supplier No. 6754/25

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Description

Potent pan-ribosomal S6 protein kinase (RSK) inhibitor (IC50 values are 4 to 13 nM)

LJI308 is a potent pan-ribosomal S6 protein kinase (RSK) inhibitor (IC50 values are 4 to 13 nM). Displays selectivity for RSK isoforms over other kinases. Inhibits RSK-dependent Y-box binding protein 1 (YB-1) phosphorylation in vitro. Suppresses growth of triple negative breast cancer cell lines.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material 2,6-Difluoro-4-[4-[4-(4-morpholinyl)phenyl]-3-pyridinyl]phenol
CAS 1627709-94-7
Quantity 25 mg
Molecular Formula C21H18F2N2O2
Formula Weight 368.38
Purity 98%
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