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Macherey-Nagel™ LIPODEX™ D Capillary Columns for GC

Enables many compounds to be analyzed without derivatization. Macherey-Nagel™ LIPODEX™ D Capillary Columns for GC are phases with seven β-cyclodextrin glucose units for enantiomer separation in gas chromatography. This lipophilic phase with long nonpolar ligants is a chemically non-bonded phase.

Brand:  Macherey-Nagel™ 723366.50

Code : 50

Additional Details : Weight : 0.01000kg

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Product Code. 10045380

  • £1626.90 / Each

Estimated Shipment: 07-03-2022
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Water as solvent is strictly forbidden for all cyclodextrin phases. It is recommended to dry the sample and dissolve it in an appropriate nonpolar solvent.



A major advantage of LIPODEX columns are that many compounds can be analyzed without derivatization. However, for certain substances, enantioselectivity can be favorably influenced by formation of derivatives. Regioselective alkylation and/or acylation of the hydroxyl groups leads to lipophilic phases with varying enantioselectivity, which are well suited for GC enantiomer analyses.

It is not possible to make a general prediction about which LIPODEX™ phase could solve a given separation task. Even for compounds with small structural differences or within homologous series, the enantiodifferentiation can be quite different.

  • Base material: cyclic oligosaccharides consisting of seven β-cyclodextrin glucose units bonded through α-1,4-linkages
  • heptakis-(2,6-di-O-pentyl-3-O-acetyl)-β-cyclodextrin
  • Ligands: R2=R6=pentyl, R3=acetyl; n=2
  • Recommended for amines (TFA), aminols (TFA), trans-cycloalkane-1,2-diols, trans-cycloalkane-1,3-diols (TFA), β-amino acid esters


0.4 mm
0.25 mm
Lipodex™ D
50 m
Non polar
GC Capillary Column
GC Enantiomer Separation
For isothermal operations: 200°C, For short isotherms in a temperature program: 220°C
Lipodex™ D
1 Each
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