Macherey-Nagel™ LIPODEX™ D Capillary Columns for GC

Enables many compounds to be analyzed without derivatization. Macherey-Nagel™ LIPODEX™ D Capillary Columns for GC are phases with seven β-cyclodextrin glucose units for enantiomer separation in gas chromatography. This lipophilic phase with long nonpolar ligants is a chemically non-bonded phase.

Brand: Macherey-Nagel™

Manufacturer Part Number: 723366.50

UNSPSC: 41115710

Code: 50

Additional Details:
Additional Details: Weight: 0.01000kg

Alerts: Water as solvent is strictly forbidden for all cyclodextrin phases. It is recommended to dry the sample and dissolve it in an appropriate nonpolar solvent.

Product Code. 10045380

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1 £ 2120.0 / Each
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Description and Specification


Technique Gas chromatography
Max. Temperature For isothermal operations: 200°C
For short isotherms in a temperature program: 220°C
Polarity Nonpolar
Diameter (Metric) Inner 0.25mm
Packing Material Lipodex® D
Stationary Phase Lipodex® D
Quantity 1Each
Product Type GC Capillary Column
Length (Metric) 50m
Diameter 0.4mm
For Use With (Application) For GC Enantiomer Separation

A major advantage of LIPODEX columns are that many compounds can be analyzed without derivatization. However, for certain substances, enantioselectivity can be favorably influenced by formation of derivatives. Regioselective alkylation and/or acylation of the hydroxyl groups leads to lipophilic phases with varying enantioselectivity, which are well suited for GC enantiomer analyses.

It is not possible to make a general prediction about which LIPODEX™ phase could solve a given separation task. Even for compounds with small structural differences or within homologous series, the enantiodifferentiation can be quite different.

  • Base material: cyclic oligosaccharides consisting of seven β-cyclodextrin glucose units bonded through α-1,4-linkages
  • heptakis-(2,6-di-O-pentyl-3-O-acetyl)-β-cyclodextrin
  • Ligands: R2=R6=pentyl, R3=acetyl; n=2
  • Recommended for amines (TFA), aminols (TFA), trans-cycloalkane-1,2-diols, trans-cycloalkane-1,3-diols (TFA), β-amino acid esters