Lincomycin hydrochloride

Product Code. 15443869

Brand: Thermo Scientific Alfa Aesar J61251.06

Description

Lincomycin hydrochloride, CAS # 859-18-7, is a compound showing antibacterial activity against a wide variety of bacteria, including Staphylococcal, Streptococcal, and Bacteroides fragilis infections. It also shows inhibitory activity against protein synthesis. | CAS: 859-18-7 | C18H35ClN2O6S | 442.996 g/mol

Lincomycin hydrochloride is used to study the inhibition of protein synthesis, bacterial antibiotic resistance and protein and surfactant binding. It has been used in the treatment of Staphylococcal, Streptococcal, and Bacterioides fragilis infections.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Lincomycin hydrochloride is a lincosamide compound with antibacterial activity originally identified in the actinomycete, Streptomyces lincolnensis, with activity against gram-positive cocci and anaerobic bacteria
• Lincomycin inhibits bacterial protein synthesis by forming cross-links within the peptidyl transferase loop region of the 23S rRNA

Application

• Lincomycin hydrochloride is commonly used to study the inhibition of protein synthesis, bacterial antibiotic resistance, and protein and surfactant binding
• It has been used against Staphylococcal, Streptococcal, and Bacteroides fragilis species
• It is protective against the development of mastitis in a mouse model of acute mastitis induced by S. aureus

Especificaciones

Identificadores de productos químicos

• CAS: 859-18-7
• Molecular Formula: C18H35ClN2O6S
• Molecular Weight (g/mol): 442.996
• MDL Number: MFCD00058237
• InChI Key: POUMFISTNHIPTI-OXVORJCQSA-N
• PubChem CID: 124080936
• IUPAC Name: (2R,4R)-N-[(1R,2R)-2-hydroxy-1-[(2S,3R,4S,5R,6S)-3,4,5-trihydroxy-6-methylsulfanyloxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide;hydrochloride
• SMILES: CCCC1CC(N(C1)C)C(=O)NC(C2C(C(C(C(O2)SC)O)O)O)C(C)O.Cl

• Type: Lincomycin Hydrochloride
• Physical Form: Crystalline Powder
• Color: White
• Quantity: 5 g
• Beilstein: 4171650
• Solubility Information: Soluble in water
• Formula Weight: 443
• Chemical Name or Material: Lincomycin hydrochloride

Seguridad y manipulación

Nombre del producto

• Lincomycin hydrochloride

Palabra de advertencia

• Warning

Clasificación

• Serious eye damage/eye irritation Category 2
• Skin corrosion/irritation Category 2
• Specific target organ toxicity Category 3

Indicaciones de peligro

• H315-Causes skin irritation.
• H319-Causes serious eye irritation.
• H335-May cause respiratory irritation.

Consejos de prudencia

• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P302+P352-IF ON SKIN: Wash with plenty of water/.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P312-Call a POISON CENTER/doctor/if you feel unwell.
• P332+P313-If skin irritation occurs: Get medical advice/attention.
• P337+P313-If eye irritation persists: Get medical advice/attention.

SDS

RUO – Research Use Only