Invitrogen™ LILRB5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA552906

Product Code. 15790851

Description

Immunogen sequence: PKPTLWAEPA SVIARGKPVT LWCQGPLETE EYRLDKEGLP WARKRQNPLE PGAKAKFHIP STVYDSAGRY RCYYETPAGW SEPSDPLELV ATG Highest antigen sequence identity to the following orthologs: Mouse - 55%, Rat - 56%.

This gene is a member of the leukocyte immunoglobulin-likereceptor (LIR) family, which is found in a gene cluster atchromosomal region 19q13.4. The encoded protein belongs to thesubfamily B class of LIR receptors which contain two or fourextracellular immunoglobulin domains, a transmembrane domain, andtwo to four cytoplasmic immunoreceptor tyrosine-based inhibitorymotifs (ITIMs). Several other LIR subfamily B receptors areexpressed on immune cells where they bind to MHC class I moleculeson antigen-presenting cells and inhibit stimulation of an immuneresponse. Multiple transcript variants encoding different isoformshave been found for this gene.

Specifications

• Antigen: LILRB5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LILRB5
• Gene Alias: CD85 antigen-like family member C; CD85C; leucocyte Ig-like receptor B5; leukocyte immunoglobulin like receptor B5; leukocyte immunoglobulin-like receptor 8; Leukocyte immunoglobulin-like receptor subfamily B member 5; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5; LILRB5; LIR8; LIR-8
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10990
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O75023
• Gene Symbols: LILRB5
• Immunogen: Recombinant protein corresponding to Human LILRB5. Recombinant protein control fragment (Product #RP-90059).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG