Invitrogen™ LILRA4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA531475

Product Code. 13475997

Description

Recommended positive controls: 293T, Raji. Predicted reactivity: Chimpanzee (97%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

ILT7 is a pDC-specific IgG-like transcript and is a member of the leukocyte immunoglobulin-like receptor gene family. This receptor, in complex with FcER1a, transduces ITAM-mediated signals which negatively modulate type I IFN production by pDC. ILT7 is thus a potential target to regulate Type 1 IFN production by pDC, which play a major role during viral infection, auto-immune diseases and anti-cancer immunity. Additionally, ILT7, along with CD123 and BDCA-2, can be used to identify or classify subsets of pDCalong with TLR expression and TLR mediated immune responses.

Specifications

• Antigen: LILRA4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LILRA4
• Gene Alias: CD85 antigen-like family member G; CD85g; ILT7; ILT-7; Immunoglobulin-like transcript 7; leucocyte Ig-like receptor A4; leukocyte immunoglobulin like receptor A4; leukocyte immunoglobulin-like receptor subfamily A member 4; leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4; leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 4; LILRA4
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23547
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.76 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P59901
• Gene Symbols: LILRA4
• Immunogen: Recombinant protein encompassing a sequence within the Extracellular domain of human LILRA4. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG