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Invitrogen™ LILRA4 Polyclonal Antibody

Description
Recommended positive controls: 293T, Raji. Predicted reactivity: Chimpanzee (97%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
ILT7 is a pDC-specific IgG-like transcript and is a member of the leukocyte immunoglobulin-like receptor gene family. This receptor, in complex with FcER1a, transduces ITAM-mediated signals which negatively modulate type I IFN production by pDC. ILT7 is thus a potential target to regulate Type 1 IFN production by pDC, which play a major role during viral infection, auto-immune diseases and anti-cancer immunity. Additionally, ILT7, along with CD123 and BDCA-2, can be used to identify or classify subsets of pDCalong with TLR expression and TLR mediated immune responses.
Specifications
Specifications
| Antigen | LILRA4 |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Polyclonal |
| Concentration | 0.76 mg/mL |
| Conjugate | Unconjugated |
| Formulation | 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7 |
| Gene | LILRA4 |
| Gene Accession No. | P59901 |
| Gene Alias | CD85 antigen-like family member G; CD85g; ILT7; ILT-7; Immunoglobulin-like transcript 7; leucocyte Ig-like receptor A4; leukocyte immunoglobulin like receptor A4; leukocyte immunoglobulin-like receptor subfamily A member 4; leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4; leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 4; LILRA4 |
| Gene Symbols | LILRA4 |
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