Lifitegrast, MedChemExpress

Artikelnummer.	Quantity	unitSize
16497738	10 mg	10mg
16433717	50 mg	50mg
16407606	100 mg	100mg

Artikelnummer. 16497738 Lieferant Medchem Express Lieferanten-Nr. HY19344

Beschreibung

MedChemExpress Lifitegrast (SAR 1118) is a potent integrin antagonist. Lifitegrast blocks the binding of intercellular adhesion molecule 1 (ICAM-1) to lymphocyte function-associated antigen 1 (LFA-1), interrupting the T cell-mediated inflammatory cycle. Lifitegrast inhibits Jurkat T cell attachment to ICAM-1 with an IC50 of 2.98 nM. Lifitegrast can be used for researching dry eye disease.

Lifitegrast (SAR 1118) is a potent integrin antagonist. Lifitegrast blocks the binding of intercellular adhesion molecule 1 (ICAM-1) to lymphocyte function-associated antigen 1 (LFA-1), interrupting the T cell-mediated inflammatory cycle. Lifitegrast inhibits Jurkat T cell attachment to ICAM-1 with an IC50 of 2.98 nM. Lifitegrast can be used for researching dry eye disease.

Spezifikation

• Chemical Name or Material: Lifitegrast
• CAS: 1025967-78-5
• Color: Off-White
• Purity Grade Notes: Research
• Molecular Formula: C₂₉H₂₄Cl₂N₂O₇S
• Quantity: 10 mg
• Synonym: SAR 1118 SHP-606
• Solubility Information: DMSO : ≥ 29 mg/mL (47.12 mM)
• SMILES: O=C(O)[C@H](CC1=CC=CC(S(=O)(C)=O)=C1)NC(C2=C(Cl)C3=C(CN(C(C4=CC=C5C=COC5=C4)=O)CC3)C=C2Cl)=O
• Molecular Weight (g/mol): 615.48
• Formula Weight: 615.48
• Percent Purity: 99.09%
• Grade: Research
• Physical Form: Solid
• For Use With (Application): COVID-19-immunoregulation

Research purposes only