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Invitrogen™ LGI3 Polyclonal Antibody

Product Code. 12828672
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Quantity:
100 μg
Unit Size:
100µg
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12828672 100 μg 100µg
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Product Code. 12828672 Supplier Invitrogen™ Supplier No. PA520494

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Description

Rabbit Polyclonal Antibody

A suggested positive control is human brain tissue lysate. PA5-20494 can be used with blocking peptide PEP-0614.

The leucine-rich, glioma inactivated gene 3 (LGI3) is a member of the LGI family in which LGI1 is the exemplar. The LGI family consists of four of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 has been identified as a candidate tumor suppressor gene for glioma and plays a role in autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Despite its high homology with LGI1 and similar pattern of expression, mutations in LGI3 have not been found to be associated with ADTLE. LGI3 expression is induced in rat astrocyte cultures by the amyloid beta (Abeta) peptide and accumulated on neuronal plasma membranes of aged monkey brains and co-localized with Abeta.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LGI3
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene Lgi3
Gene Accession No. Q8K406, Q8N145
Gene Alias AI841179; AW049851; Leubrin; leucine rich repeat LGI family member 3; leucine-rich glioma-inactivated protein 3; Leucine-rich repeat LGI family member 3; leucine-rich repeat LGI family, member 3; LGI1-like protein 4; LGI3; LGIL4; UNQ8190/PRO23199
Gene Symbols Lgi3
Host Species Rabbit
Immunogen a 12 amino acid peptide from near the center of human LGI3.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 203190, 213469, 306013
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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