Invitrogen™ LGI2 Monoclonal Antibody (748914)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA561805

Product Code. 30534166

Description

Reconstitute with sterile PBS to a final concentration of 0.5 mg/mL.

The leucine-rich, glioma inactivated gene 2 (LGI2) is a member of the LGI family in which LGI1 is the exemplar. The LGI family consists of four of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 has been identified as a candidate tumor suppressor gene for glioma and plays a role in autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Despite its high homology with LGI1 and similar pattern of expression, mutations in LGI2 have not been found to be associated with ADTLE.

Specifications

• Antigen: LGI2
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with trehalose and no preservative
• Gene Accession No.: Q8N0V4
• Gene Symbols: Lgi2
• Immunogen: Chinese hamster ovary cell line CHO-derived recombinant human LGI2, Gln29-Ser276.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Western Blot, Immunocytochemistry
• Clone: 748914
• Conjugate: Unconjugated
• Gene: Lgi2
• Gene Alias: Kiaa1916; leucine rich repeat LGI family member 2; leucine-rich glioma-inactivated protein 2; Leucine-rich repeat LGI family member 2; leucine-rich repeat LGI family, member 2; leucine-rich, glioma inactivated 2; LGI1-like protein 2; Lgi2; LGIL2; mKIAA1916
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 55203
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Lyophilized